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What Does Ivermectin Do to the Brain?

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  • What Does Ivermectin Do to the Brain?

    Ivermectin Iverheal 12mg can affect the brain by binding to glutamate-gated chloride channels, which are abundant in parasites but less so in humans. In mammals, the blood-brain barrier (BBB) generally prevents ivermectin from entering the central nervous system (CNS) by blocking large molecules from crossing into brain tissue. However, in rare cases where the BBB is compromised, or in individuals with specific genetic mutations (e.g., MDR1 gene defects), ivermectin may penetrate the CNS and cause neurological effects.

    Adverse effects on the brain, though uncommon, can include dizziness, confusion, tremors, ataxia, or even seizures. These symptoms are more likely when ivermectin is taken in excessive doses or in sensitive populations, such as certain dog breeds with genetic susceptibility to ivermectin toxicity (e.g., Collies). The risk in humans is typically low when the drug is used at approved doses for treating parasitic infections.

    Research continues to explore ivermectin’s potential neurological impacts, particularly in experimental studies where higher doses may have effects on neurotransmitter pathways. In summary, while ivermectin’s primary action targets parasites, its interaction with the human brain is generally minimal due to the protective nature of the BBB, barring specific vulnerabilities.
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