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Introduction:
3-Dimethylamino-propyl)-ethyl-carbodiimide Hydrochloride, commonly referred to as EDC, is a chemical reagent widely used in bioconjugation, peptide synthesis, and drug delivery applications. This informative piece aims to delve into the properties, synthesis, applications, and safety considerations of EDC.
Chemical Structure and Properties:
EDC features a carbodiimide functional group and is typically found in its hydrochloride salt form. It exhibits characteristics such as solubility in polar solvents and stability under appropriate conditions. Understanding these properties is crucial for its effective utilization in various chemical reactions.
Synthesis and Manufacturing:
The synthesis of EDC often involves the condensation reaction between N,N'-dicyclohexylcarbodiimide (DCC) and N,N-dimethylaminopropylamine. EDC HCL Manufacturing processes are designed to optimize yield, purity, and consistency, ensuring the quality of EDC products for research and industrial purposes.
Applications in Bioconjugation and Peptide Synthesis:
EDC plays a pivotal role in bioconjugation reactions by facilitating the covalent coupling of carboxyl-containing molecules with primary amines. In peptide synthesis, it activates carboxyl groups for amide bond formation, enabling the efficient synthesis of peptides and proteins.
3-Dimethylamino-propyl)-ethyl-carbodiimide Hydrochloride, commonly referred to as EDC, is a chemical reagent widely used in bioconjugation, peptide synthesis, and drug delivery applications. This informative piece aims to delve into the properties, synthesis, applications, and safety considerations of EDC.
Chemical Structure and Properties:
EDC features a carbodiimide functional group and is typically found in its hydrochloride salt form. It exhibits characteristics such as solubility in polar solvents and stability under appropriate conditions. Understanding these properties is crucial for its effective utilization in various chemical reactions.
Synthesis and Manufacturing:
The synthesis of EDC often involves the condensation reaction between N,N'-dicyclohexylcarbodiimide (DCC) and N,N-dimethylaminopropylamine. EDC HCL Manufacturing processes are designed to optimize yield, purity, and consistency, ensuring the quality of EDC products for research and industrial purposes.
Applications in Bioconjugation and Peptide Synthesis:
EDC plays a pivotal role in bioconjugation reactions by facilitating the covalent coupling of carboxyl-containing molecules with primary amines. In peptide synthesis, it activates carboxyl groups for amide bond formation, enabling the efficient synthesis of peptides and proteins.