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Ceftriaxone injection is prescribed for serious bacterial infections when oral antibiotics are ineffective or unsuitable. It’s used for conditions like meningitis, pneumonia, sepsis, urinary tract infections, bone/joint infections, and intra-abdominal infections caused by susceptible bacteria. The ceftriaxone injection is also indicated for gonorrhea and endocarditis in specific cases. It’s typically reserved for hospitalized patients or outpatient treatment under medical supervision due to its potency and administration route. Prescribing depends on infection severity, bacterial sensitivity, and patient factors like allergies or kidney function. Always confirm with culture results when possible to ensure targeted therapy and avoid resistance.