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Men with erectile dysfunction (ED) are the main patients for the combo drug Sildalist 120 mg. Tadalafil (20 mg) and sildenafil citrate (100 mg) are its two active components. Both tadalafil, sometimes marketed as Cialis, and sildenafil, often referred to as Viagra, are phosphodiesterase type 5 (PDE5) inhibitors. By boosting blood flow to the penis during sexual stimulation, these ingredients combine to improve erectile function. Aurogra 100 and Malegra 200 are ED treatments with sildenafil citrate, enhancing blood flow for erections.
Cyclic guanosine monophosphate (cGMP) is broken down by the PDE5 enzyme, which is inhibited as part of the mechanism of action. In the penile tissue, cGMP is a chemical that dilates blood vessels and relaxes smooth muscle cells. Inhibiting PDE5 raises cGMP levels, which prolong muscular relaxation and improve blood flow. These effects make it easier to obtain and sustain an erection.
By combining the longer duration of tadalafil with the quick onset effect of sildenafil, sildalist 120mg offers two benefits. Tadalafil may take up to two hours to start working, but it can last up to 36 hours. Sildenafil usually takes thirty minutes to an hour to start working. More flexibility and spontaneity in sexual activity are made possible by this combination.
Cyclic guanosine monophosphate (cGMP) is broken down by the PDE5 enzyme, which is inhibited as part of the mechanism of action. In the penile tissue, cGMP is a chemical that dilates blood vessels and relaxes smooth muscle cells. Inhibiting PDE5 raises cGMP levels, which prolong muscular relaxation and improve blood flow. These effects make it easier to obtain and sustain an erection.
By combining the longer duration of tadalafil with the quick onset effect of sildenafil, sildalist 120mg offers two benefits. Tadalafil may take up to two hours to start working, but it can last up to 36 hours. Sildenafil usually takes thirty minutes to an hour to start working. More flexibility and spontaneity in sexual activity are made possible by this combination.